Rapid eye movement sleep behavior disorder clusters within families and links to neurodegeneration

Takeaway

  • Early biomarkers of neurodegenerative diseases were found in family members of people with rapid eye movement (REM) sleep behavior disorder (RBD).

Why this matters ?

  • RBD is itself a prodromal marker of early onset Parkinson’s Disorder (PD) and these findings suggest that the pathogenesis, either genetic and/or environmental, of RBD is associated with neurodegeneration.