Myelin oligodendrocyte glycoprotein antibody in patients with uveitis or optic perineuritis

Takeaway

  • Antibody to myelin oligodendrocyte glycoprotein (MOG) can be present in some patients with inflammatory ophthalmic conditions other than optic neuritis (ON); MOG antibody testing should be considered in these diagnostically difficult cases.

Why this matters

  • Identification of MOG antibody in patients with non-ON ophthalmic conditions may expand the clinical spectrum of MOG antibody-associated presentations.