Damage to long-range brain connections impacts cognition in multiple sclerosis

Takeaway

  • Compared with multiple sclerosis (MS)-specific short-range connections in the brain, MS-specific damage to long-range connections is more severe and more strongly related with reduced efficiency of structural networks and impact on cognitive function.

Why this matters

    These results better our understanding of how MS-specific damage brings about cognitive impairment and may inform future developments in understanding disease prognosis.