Can low-contrast visual evoked potential help detect optic nerve abnormality in multiple sclerosis?

Takeaway

  • Low-contrast visual evoked potential (VEP) is not superior to conventional VEP for detection of early-stage optic nerve abnormality in multiple sclerosis (MS).

Why this matters

  • VEP is a useful alternative to magnetic resonance imaging for detection of optic nerve demyelination in early-stage MS, but conventional VEP techniques lack sensitivity.